Carboxylic acids and derivatives
Medchemexpress LLC Arimoclomol citrate 5mg | 368860-21-3 | 5MG
Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins (HSP)[1 Arimoclomol citrate protects motor neurons by enhancing Hsp expression thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system[2 Arimoclomol citrate can be used for the study of Niemann Pick disease type C
Medchemexpress LLC Azido-PEG6-CH2COOH | 880129-82-8 | ≥98.0% | 365.38 | 1 G
Azido-PEG6-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is a click chemistry reagent, featuring an azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It also facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- Functions as a PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Integral to PROTACs that selectively degrade target proteins
Sigma Aldrich Fine Chemicals Biosciences Trisodium citrate dihydrate meets USP testing specifications | 6132-04-3 | MFCD00150031 | 1KG
Trisodium citrate dihydrate meets USP testing specifications | Purity: 99.0-100.5% anhydrous basis | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 1KG
Medchemexpress LLC IACS-8803 diammonium | 98.8% | 50 MG
IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist known for its robust systemic antitumor efficacy. It has demonstrated superior antitumor activity in in-vivo studies, specifically in mice bearing bilateral B16-OVA melanomas with a 10 μg intra-tumoral injection.
- Highly potent cyclic dinucleotide STING agonist
- Robust systemic antitumor efficacy
- Molecular weight: 726.60
- Molecular formula: C20H29FN12O9P2S2
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC diMal-O-CH2COOH | 1620837-47-9 | 96.8% | C13H12N2O7 | 5 MG
diMal-O-CH2COOH is a cleavable ADC linker, intended for research use only.
- Solid appearance, white to off-white color.
- Shipping at room temperature in continental US.
- Store at 4°C, protected from light and under nitrogen.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen.
- Relevant for cancer and cancer targeted therapy research.